## Drug Name Clopidogrel (Plavix) ## Drug Class Antiplatelet Agent ## Indications Clopidogrel is used to prevent blood clots in patients with recent heart attack, stroke, or peripheral artery disease. It is also prescribed to prevent blood clots in patients with certain heart or blood vessel conditions. ## Common Side Effects - Easy bruising - Minor bleeding - Stomach upset ## Serious Side Effects - Severe bleeding - Thrombotic Thrombocytopenic Purpura (TTP) - Neutropenia ## Warnings / Contraindications Clopidogrel may increase the risk of bleeding, especially in individuals with certain medical conditions like peptic ulcer disease or recent surgery. It should be used with caution in patients at risk for bleeding. ## Dosage Forms - Tablet: 75 mg, 300 mg ## Pharmacy Technician Notes - **Key Counseling Points:** Advise patients to report any signs of bleeding or bruising promptly. Inform patients about the increased risk of bleeding with certain medications like NSAIDs or anticoagulants. - **Interactions:** Clopidogrel may interact with proton pump inhibitors (PPIs) reducing its effectiveness. Monitor for this interaction. - **Monitoring:** Regularly monitor platelet count and signs of bleeding in patients on clopidogrel therapy. ## Summary Clopidogrel (Plavix) is an essential antiplatelet agent used in cardiovascular care to prevent blood clots in high-risk patients. It plays a crucial role in reducing the risk of heart attacks, strokes, and other cardiovascular events. Patients should be educated about the importance of medication adherence, signs of bleeding, and potential drug interactions to ensure safe and effective therapy.