## Drug NameClopidogrel (Plavix)## Drug ClassAntiplatelet Agent## IndicationsClopidogrel is commonly used to prevent blood clots in patients with a history of cardiovascular events such as myocardial infarction or stroke. It is also prescribed for patients undergoing stent placement to prevent stent thrombosis.## Common Side Effects- Easy bruising- Bleeding more easily than usual- Headache- Diarrhea## Serious Side Effects- Severe bleeding (e.g., gastrointestinal bleeding, intracranial bleeding)- Thrombotic thrombocytopenic purpura (TTP) - a rare blood disorder## Warnings / Contraindications- Clopidogrel may increase the risk of bleeding, especially when combined with other blood-thinning medications.- Contraindicated in patients with active bleeding, severe liver disease, and a history of TTP.## Dosage Forms- Tablet: Available in various strengths (e.g., 75 mg, 300 mg)## Pharmacy Technician Notes- Counsel patients to report any signs of bleeding such as black or tarry stools, blood in urine, or unusual bleeding.- Inform patients about the importance of compliance with therapy to prevent blood clots.- Monitor for signs of TTP, such as unexplained bruising or petechiae.## SummaryClopidogrel, sold under the brand name Plavix, is a vital medication in cardiovascular care. It helps prevent blood clots that can lead to serious events like heart attacks and strokes. Patients should be aware of the increased risk of bleeding while taking this medication and should promptly report any unusual bleeding or bruising to their healthcare provider. Counseling on the importance of adherence to therapy and monitoring for adverse effects is crucial for optimal patient outcomes.